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Found 146 Enz. Inhib. hit(s) with Target = 'Cholesterol 24-hydroxylase'
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590454(CHEMBL5195220)
Affinity DataKi:  13nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590453(CHEMBL5186695)
Affinity DataKi:  106nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590452(CHEMBL5206380)
Affinity DataKi:  258nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50545375(CHEMBL4527162)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity to full length human CYP46A1 expressed in Escherichia coli DH5alpha as cholesterol-24 hydroxylation using cholesterol as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609199(CHEMBL5279173)
Affinity DataIC50:  1nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609193(CHEMBL5288661)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609182(CHEMBL5276973)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609197(CHEMBL5282804)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609191(CHEMBL5271033)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609194(CHEMBL5269674)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393292(US9963443, Reference Example 21)
Affinity DataIC50:  4.90nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609189(CHEMBL5289771)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393278(US9963443, Reference Example 1)
Affinity DataIC50:  5.40nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609195(CHEMBL5284673)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393291(US9963443, Reference Example 20)
Affinity DataIC50:  6.90nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393282(US9963443, Reference Example 4)
Affinity DataIC50:  7.10nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583509(CHEMBL5093928)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583519(OV-935 | OV935 | SOTICLESTAT | Soticlestat | TAK-9...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393280(US9963443, Reference Example 3)
Affinity DataIC50:  7.40nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583519(OV-935 | OV935 | SOTICLESTAT | Soticlestat | TAK-9...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609192(CHEMBL5275089)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609196(CHEMBL5275183)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583501(CHEMBL4594072)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583512(CHEMBL4532699)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393279(US9963443, Reference Example 2)
Affinity DataIC50:  8.80nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583515(CHEMBL4527933)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393297(US9963443, Reference Example 26)
Affinity DataIC50:  10nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583518(CHEMBL5083867)
Affinity DataIC50:  12nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583517(CHEMBL4538165)
Affinity DataIC50:  12nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583508(CHEMBL5076011)
Affinity DataIC50:  14nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609181(CHEMBL5286208)
Affinity DataIC50:  16nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393285(US9963443, Reference Example 11)
Affinity DataIC50:  16nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583507(CHEMBL5082831)
Affinity DataIC50:  16nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609188(CHEMBL5274224)
Affinity DataIC50:  17nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393296(US9963443, Reference Example 23)
Affinity DataIC50:  17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393288(US9963443, Reference Example 14)
Affinity DataIC50:  17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393283(US9963443, Reference Example 5)
Affinity DataIC50:  19nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393284(US9963443, Reference Example 10)
Affinity DataIC50:  20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM393286(US9963443, Reference Example 13)
Affinity DataIC50:  20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609198(CHEMBL5269081)
Affinity DataIC50:  21nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583514(CHEMBL4580834)
Affinity DataIC50:  24nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583506(CHEMBL5087082)
Affinity DataIC50:  28nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609201(CHEMBL5272679)
Affinity DataIC50:  36nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583503(CHEMBL4561003)
Affinity DataIC50:  44nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583511(CHEMBL5083692)
Affinity DataIC50:  48nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583499(CHEMBL4555625)
Affinity DataIC50:  52nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583505(CHEMBL5094350)
Affinity DataIC50:  58nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50609203(CHEMBL5285548)
Affinity DataIC50:  60nMAssay Description:Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as s...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583516(CHEMBL5082660)
Affinity DataIC50:  65nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50583510(CHEMBL5080231)
Affinity DataIC50:  68nMAssay Description:Inhibition of CH24H expressing human 293-F cells for 15 minutes using [14C] cholesterol as substrate and measured after 5 hrs by trypan blue staining...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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